Program

Carcinogenesis, Genome stability, DNA damage and Repair
Chair: L. Wiesmüller (Ulm), M. Schwarz (Tübingen)
M. Digweed (Berlin):  DNA-Repair deficiency and carcinogenesis: lessons from Nijmegen Breakage Syndrome
J. Klefström (Helsinki): Determinants of cell polarity in development of cancer
A. Csernok (Ulm):  DNA double strand break repair dysfunction as a marker for the identification of enhanced breast cancer risk
M. Hoffmann (Düsseldorf):  Role of the Rho-like GTPase Rac3 in prostate carcinogenesis

Genetic and Epigenetic Factors Controlling Tumor Progression and Metastasis
Chair: C. Sers (Berlin), B. Groner (Frankfurt)
A. Fusco (Naples): Molecular mechanisms of thyroid cancer progression
C. Müller-Tidow (Münster): Epigenetic regulation of metastasis in non-small cell lung cancer
M. Emadi-Baygi (Teheran):  Nonredundant and unexpected functions of the EMT-regulatory transcription factors Snail and Slug in prostate cancer cell lines
A. Malek:  HMGA2 is a promising target for ovarian carcinoma silencing therapy

Tumor Stem Cells
Chair: P. Boukamp (Heidelberg), A. Trumpp (Heidelberg)
A. Trumpp (Lausanne): Dormant and activated stem cells during homeostasis, injury and cancer
C. Herold-Mende (Heidelberg):  Monitoring antitumorigenic effects of differentiation on brain tumor stem cells in vivo using intravital microscopy
D. Dorn (New York):  Specific targeting of leukemic stem cell engraftment by the CXCR4 antagonist CTCE-9908

German Cancer Society – Cancer Awards
W. Hohenberger (Erlangen), R. Schäfer (Berlin),  H.-H. Kreipe (Hannover)T. Klingebiel (Frankfurt)

Certification of the Charité Comprehensive Cancer Center

Tumor Stem Cells (continued)
B. Groner (Frankfurt): Stat5 activation in mammary stem cells cooperates with pregnancy hormones and causes tumor formation

Reception and Buffet